Table-II.

Summary of comparisons based on different genotypes

		Sample size		No. of	Test of association
	Study	case	control	studies	OR (95% CI)	Z	P value
AA + AG vs. GG	Overall	1529	2399	10	1.62 (1.23 – 2.12)	3.47	0.0005
	Asian	908	784	5	1.87 (1.20 – 2.91)	2.78	0.005
	Caucasian	621	1615	5	1.41 (1.02 – 1.94)	2.08	0.04
AA vs. AG + GG	Overall	1252	2188	9	1.48 (1.02 – 2.15)	2.09	0.04
	Asian	631	573	4	1.42 (0.92 – 3.26)	1.69	0.09
	Caucasian	621	1615	5	1.31 (0.79 – 2.18)	1.05	0.29
AA vs. GG	Overall	685	1216	9	1.77 (1.11 – 2.82)	2.41	0.02
	Asian	366	343	4	2.14 (0.96 – 4.81)	1.85	0.06
	Caucasian	319	873	5	1.53 (0.82 – 2.86)	1.33	0.18
AG vs. GG	Overall	999	1885	9	1.37 (1.14 – 1.64)	3.43	0.0006
	Asian	461	453	4	1.36 (1.04 – 1.78)	2.26	0.02
	Caucasian	538	1432	5	1.37 (1.08 – 1.75)	2.58	0.01
A vs. G	Overall	2504	4376	9	1.40 (1.10 – 1.78)	2.72	0.006
	Asian	1262	1146	4	1.60 (1.00 – 2.57)	1.97	0.05
	Caucasian	1242	3230	5	1.27 (0.96 – 1.68)	1.70	0.09