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. Author manuscript; available in PMC: 2014 Dec 19.
Published in final edited form as: Cell. 2013 Dec 19;155(7):1507–1520. doi: 10.1016/j.cell.2013.11.039

Figure 3. Gene clusters identified by ChIA-PET.

Figure 3

(A) Single-promoter clusters in activated B cells connecting 1,231 gene promoters to at least one enhancer. Right: e.g. the Gpr183 promoter (blue circle) is linked to 12 enhancers (red circles) via 76 interactions. PETs anchored outside enhancers are represented with grey circles. Circles are sized according to the absolute number of anchored PETs. (B) Interactions at the Cd83 single gene cluster. (C) Multi-promoter clusters (n = 1,481) identified in B cells. The Rela cluster display 398 interactions involving 66 genes. (D) PolII connections between lncRNA E85930, Clec2d, and Cd69. Promoters and enhancers are boxed and number of PETs are provided in parenthesis. (E) Transcription levels of genes associated with trace (no detectable FPKM), low (<0.9 FPKM), or highly transcribed lncRNAs (≥0.9 FPKM).