Table 6.
Week 28 Outcome Measures by BMI Class (given as N(%) or mean ± std)
| NW | OW | OB1 | OB2+ | Unadjusted OR** | p | Adjusted OR** | p | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Remission | 76 (45.0) | 84 (44.9) | 57 (42.9) | 81 (46.8) | 0.93 | 0.97 | 1.08 | 0.93 | 0.89 | 0.95 | 1.08 | 0.88 |
| Last QIDS-SR <6 | 82 (49.1) | 81 (43.5) | 55 (42.0) | 74 (43.3) | 0.79 | 0.72 | 0.81 | 0.60 | 0.79 | 0.72 | 0.83 | 0.70 |
| Response | 99 (60.7) | 105 (58.0) | 68 (52.7) | 101 (61.6) | 0.88 | 0.66 | 0.96 | 0.37 | 0.85 | 0.63 | 0.96 | 0.31 |
| Last QIDS-SR | 7.9 ± 6.2 | 7.5 ± 5.2 | 7.7 ± 5.5 | 7.2 ±5.3 | 1.06 | 1.06 | 0.98 | 0.84 | 1.06 | 1.07 | 0.98 | 0.78 |
| % drop in QIDS-SR | 49 ± 37.5 | 50 ± 34.3 | 47 ± 36.5 | 53 ± 32.5 | −1.14 | 3.10 | −3.08 | 0.56 | −1.33 | 3.33 | −3.51 | 0.47 |
| Exited Continuation Phase | 68 (40.2) | 76 (40.6) | 48 (36.1) | 51 (29.5) | 1.11 | 0.84 | 0.63 | 0.11 | 1.21 | 0.95 | 0.73 | 0.25 |
| Max FISBER Frequency | 0.87 | 0.63 | 0.49 | 0.004 | 0.82 | 0.57 | 0.47 | 0.009 | ||||
| No SE’s | 12 (7.5) | 24 (13.4) | 19 (15.1) | 27 (16.4) | ||||||||
| 10–25% (time) | 44 (27.5) | 52 (25.1) | 44 (34.9) | 59 (35.8) | ||||||||
| 50–75% | 60 (37.5) | 57 (31.8) | 34 (27.0) | 58 (35.2) | ||||||||
| 90–100% | 44 (27.5) | 53 (29.6) | 29 (23.0) | 21 (12.7) | ||||||||
| Max FIBSER Intensity | 0.98 | 0.77 | 0.52 | 0.010 | 1.00 | 0.79 | 0.57 | 0.056 | ||||
| None | 12 (7.5) | 22 (12.3) | 14 (11.1) | 26 (15.8) | ||||||||
| Minimal/Mild | 41 (25.6) | 44 (24.6) | 41 (32.5) | 57 (34.5) | ||||||||
| Moderate/Marked | 76 (47.5) | 76 (42.5) | 53 (42.1) | 60 (36.4) | ||||||||
| Severe/Intolerable | 31 (19.4) | 37 (20.7) | 18 (14.3) | 22 (13.3) | ||||||||
| Max FIBSER Burden | 0.95 | 0.80 | 0.59 | 0.069 | 0.90 | 0.77 | 0.56 | 0.091 | ||||
| None | 17 (10.6) | 36 (20.1) | 22 (17.5) | 39 (23.6) | ||||||||
| Minimal/Mild | 75 (46.9) | 64 (35.8) | 60 (47.6) | 70 (42.4) | ||||||||
| Moderate/Marked | 48 (30.0) | 55 (30.7) | 34 (27.0) | 45 (27.3) | ||||||||
| Severe/Intolerable | 20 (12.5) | 24 (13.4) | 10 (7.9) | 11 (6.7) | ||||||||
| Last FISBER Frequency | 1.21 | 0.63 | 0.50 | <0.001 | 1.34 | 0.72 | 0.63 | 0.009 | ||||
| No SE’s | 69 (43.1) | 80 (44.9) | 67 (53.2) | 96 (58.5) | ||||||||
| 10–25% (time) | 62 (38.8) | 59 (33.1) | 45 (35.7) | 52 (31.7) | ||||||||
| 50–75% | 16 (10.0) | 27 (15.2) | 12 (9.5) | 14 (8.5) | ||||||||
| 90–100% | 13 (8.1) | 12 (6.7) | 2 (1.6) | 2 (1.2) | ||||||||
| Last FIBSER Intensity | 1.21 | 0.62 | 0.51 | <0.001 | 1.32 | 0.69 | 0.63 | 0.001 | ||||
| None | 68(45.2) | 80(44.9) | 69(54.8) | 94(57.3) | ||||||||
| Minimal/Mild | 61(38.1) | 56(31.5) | 41(32.5) | 53(32.3) | ||||||||
| Moderate/Marked | 22(13.8) | 35(19.7) | 12(9.5) | 14(8.5) | ||||||||
| Severe/Intolerable | 9(5.6) | 7(3.9) | 2(1.6) | 3(1.8) | ||||||||
| Last FIBSER Burden | ||||||||||||
| None | 84(52.5) | 98(55.1) | 78(61.9) | 113(68.9) | 0.97 | 0.64 | 0.42 | 0.002 | 1.01 | 0.69 | 0.47 | 0.017 |
| Minimal/Mild | 51(31.9) | 57(32.0) | 34(27.0) | 41(25) | ||||||||
| Moderate/Marked | 20(12.5) | 17(9.6) | 12(9.5) | 9(5.5) | ||||||||
| Severe/Intolerable | 5(3.1) | 6(3.4) | 2(1.6) | 1(0.6) | ||||||||
NOTE Models assume either OR=1 or β=1 for reference category of the analysis variable.
*
Adjusted for treatment, systolic BP, pulse, PDSQ PTSD and SUD, N treated SCQ health problems, clinical setting, and atypical features.
**
Or for continuous measures, β
†
Models are unestimable.
‡
An extremely non-normal distribution required binning.