Table VI.
The effect of photodynamic therapy (PDT) on other sphingolipids in siControl- and siDES-transfected cells.
| 250 nM Pc 4 /PDT FDR* |
Fold-change† | 500 nM Pc 4 /PDT FDR* |
Fold-change† | |
|---|---|---|---|---|
| siControl | ||||
| Dihydrosphingosine | 0.0001 | 6.86** | 1.5E-06 | 17.01** |
| Sphingosine | 0.002 | 3.45 | 6.3E-07 | 41.07 |
| siDES | ||||
| Dihydrosphingosine | 4.0E-05 | 4.18 | 1.1E-06 | 8.13 |
| Sphingosine | 0.001 | 3.85 | 9.0E-07 | 44.26 |
†
Post-PDT relative to that in untreated controls.
*
Adjusted p-values using the false discovery rate (FDR) adjustment algorithm.
**
Higher in siControl-transfected cells. DES, Dihydroceramide desaturase 1.