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. Author manuscript; available in PMC: 2014 Jan 29.
Published in final edited form as: Anticancer Res. 2013 Jan;33(1):77–84.

Table VI.

The effect of photodynamic therapy (PDT) on other sphingolipids in siControl- and siDES-transfected cells.

250 nM Pc 4 /PDT
FDR*
Fold-change 500 nM Pc 4 /PDT
FDR*
Fold-change
siControl
Dihydrosphingosine 0.0001 6.86** 1.5E-06 17.01**
Sphingosine 0.002 3.45 6.3E-07 41.07
siDES
Dihydrosphingosine 4.0E-05 4.18 1.1E-06 8.13
Sphingosine 0.001 3.85 9.0E-07 44.26

Post-PDT relative to that in untreated controls.

*

Adjusted p-values using the false discovery rate (FDR) adjustment algorithm.

**

Higher in siControl-transfected cells. DES, Dihydroceramide desaturase 1.