Table 4.
Haplotypes of PPARγ rs1805192 and rs3856806 polymorphisms and association withdyslipidemia, TC and TG levels
| rs1805192 | rs3856806 | Frequency | Difference (95CI%) | P-value | |
|---|---|---|---|---|---|
| Dyslipidemia |
Pro |
C |
0.5393 |
1 |
- |
| |
Pro |
T |
0.196 |
1.90 (1.33 ~ 2.71) |
<0.001 |
| |
Ala |
C |
0.1692 |
2.17 (1.53 ~ 3.09) |
<0.001 |
| |
Ala |
T |
0.0954 |
2.06 (1.36 ~ 3.12) |
<0.001 |
| |
rs1805192 |
rs3856806 |
Frequency |
Difference (95CI%) |
P-value |
| Total cholesterol |
Pro |
C |
0.5395 |
0 |
- |
| |
Pro |
T |
0.1959 |
0.15 (0.00 ~ 0.30) |
0.06 |
| |
Ala |
C |
0.1691 |
0.09 (-0.07 ~ 0.25) |
0.29 |
| |
Ala |
T |
0.0956 |
0.29 (0.09 ~ 0.48) |
<0.001 |
| |
rs1805192 |
rs3856806 |
Frequency |
Difference (95CI%) |
P-value |
| Triglyceride |
Pro |
C |
0.539 |
0 |
- |
| |
Pro |
T |
0.1963 |
0.6 (0.32 ~ 0.88) |
<0.001 |
| |
Ala |
C |
0.1695 |
0.87 (0.58 ~ 1.17) |
<0.001 |
| Ala | T | 0.0951 | 0.94 (0.57 ~ 1.3) | <0.001 |
Adjusted for gender, age, smoking, alcohol consumption, BMI and waist circumference.