Table 4.

Health-related quality of life.

Study	Subjects	Setting	Outcomes studied	Race- or SES-based differences identified?	Relevant data
Bernklev, 200629	N=495 CD=161 UC=334	IBD outpatients in population-based prospective cohort in Norway	• HRQOL (using SF-36 and the Norway-IBDQ)	Yes (SES)	• Unemployment and disability status were associated with reduced HRQOL
Casellas, 200230	N=354 CD=169 UC=185	IBD outpatients from a single university-based clinic in Spain	• HRQOL (using IBDQ)	Yes (SES)	• Higher education level associated with higher IBDQ score
Feagan, 200531	N=573	CD outpatients enrolled in clinical trial	• HRQOL (using IBDQ and SF-36)	Yes (SES)	• Mean IBDQ score 121.8 for unemployed subjects versus 133.4 for employed subjects • Mean SF-36 physical health score 31.1 for unemployed subjects versus 36 for employed subjects • Mean SF-36 mental health score 37.4 for unemployed subjects versus 40.2 for employed subjects
Iglesias, 200932	N=92	CD outpatients in remission enrolled in prospective cohort	• HRQOL (using SF-36)	Yes (SES)	• Lower education level associated with lower SF-36 score
Maunder, 200733	N=155	UC outpatients recruited directly for study	• “Illness intrusiveness” via validated scale	Yes (SES)	• UC more intrusive among unmarried subjects versus married subjects
Rubin, 200434	N=409	IBD outpatients in the United Kingdom	• HRQOL (using IBDQ)	Yes (SES)	• Subjects from lowest geographic income quintile had 9-point lower IBDQ score
Straus, 200035	N=552 AA=145 W=407	CD outpatients recruited from multiple clinics	• HRQOL (SF-36)	No (race)	• No differences in disease severity • SF-36 score 56.3 in AA versus 61.1 in W, but P=NS in adjusted analysis

AA, African Americans; CD, Crohn's disease; HRQOL, health-related quality of life; IBD, inflammatory bowel disease; IBDQ, Inflammatory Bowel Disease Questionnaire; SF-36, Short Form-36 Health Survey; SES, socioeconomic status; UC, ulcerative colitis; W, white