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. 2014 Jan;14(1):69–95. doi: 10.2174/15665240113136660079

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© 2013 Bentham Science Publishers

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. (10) — Linear IgA disease. (a) Erythema, blisters, erosions and crusts in a 4-year old child with linear IgA disease. (b) Histopathological examination reveals subepidermal cleavage and a rich inflammatory infiltrate dominated by neutrophils. (c) Direct immunofluorescence microscopy analysis of perilesional skin shows linear IgA deposition at the dermo-epidermal junction. (d) Serum IgA-autoantibodies bind to the epidermal side of 1M NaCl-split skin by indirect immunofluorescence microscopy (all magnification 200x).