Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Diagnostic Criteria for Pemphigus Foliaceus
| Investigation | Finding |
|---|---|
| Clinic | Fragile blisters, crusty erosions (seborrhoeic areas) |
| Histology | Subcorneal cleavage with acantholysis |
| Direct immunofluorescence microscopy | Intraepidermal deposits of IgG (+/- C3) with an intercellular pattern |
| Indirect immunofluorescence microscopy (esophagus) | Binding of IgG autoantibodies to epithelial cells with an intercellular pattern |
| ELISA | Desmoglein 1-specific IgG autoantibodies |
