Table 8.

Diagnostic Criteria for IgA Pemphigus

Investigation	Finding
Clinic	Vesiculopustular eruption.
Histology	Intraepidermal pustules with low acantholysis and neutrophilic infiltrates in the epidermis and upper dermis
Direct immunofluorescence (IF) microscopy	Epidermal IgA deposits with an intercellular pattern
Indirect IF microscopy (esophagus)	Binding of IgA autoantibodies to epithelial cells with an intercellular pattern
Indirect IF microscopy (desmocollin-transfected COS-7 cells)/ELISA	IgA autoantibodies against desmocollins 1-3