Patterns of cytomegalovirus (CMV) replication and associations between different maternal compartments. A, Patterns of CMV detection in 142 human immunodeficiency virus type 1 (HIV-1)–infected women with sampling in all compartments. B, Individual plots of the 7 subjects with CMV detected in all compartments. C, Schematic showing correlations between CMV replication in different maternal compartments. Odds ratios and beta coefficients (β) derived from regression models showing detection of CMV DNA in plasma at 34 weeks gestation as a predictor of cervical CMV DNA detection and CMV DNA levels in breast milk, and detection of CMV DNA in cervix 34 weeks gestation as a predictor of CMV DNA levels in breast milk. All estimates adjust for treatment allocation and plasma HIV-1 RNA level. Abbreviations: CI, confidence interval; CMV, cytomegalovirus; OR, odds ratio; P, weeks gestation of pregnancy; W, weeks postpartum.