Table 2.
Neuropsychological test scores (mean ± SD) in normal controls (NC) and female FXTAS patients (with education controlled for as a covariate).
NC (N = 27) | FXTAS (N = 34) | F | p | |
---|---|---|---|---|
Global Abilities | ||||
MMSE | 28.2 ± 2.2 | 27.7 ± 1.6 | 1.39 | 0.24 |
Executive Function | ||||
COWAT | 50.0 ± 15.2 | 41.2 ± 11.9 | 4.34 | 0.04# |
BDS-2 | 21.7 ± 3.6 | 16.2 ± 3.5 | 20.85 | < 0.0001*** |
Stroop | 43.2 ± 8.0 | 32.3 ± 10.0 | 14.53 | < 0.001** |
Verbal memory | ||||
CVLT List A, trials 1–5 | 53.6 ± 8.6 | 45.1 ± 9.5 | 7.46 | 0.009* |
CVLT SD FR | 11.2 ± 3.1 | 9.33 ± 3.4 | 3.68 | 0.06# |
CVLT SD CR | 12.0 ± 2.6 | 10.6 ± 2.7 | 2.19 | 0.15 |
CVLD LD FR | 11.1 ± 2.8 | 9.6 ± 3.6 | 2.23 | 0.14 |
CVLT LD CR | 11.8 ± 2.5 | 10.7 ± 2.7 | 1.51 | 0.23 |
Subsequent Memory (for ERP Stimuli) | ||||
Free Recall | 21.6 ± 9.3 | 18.9 ± 9.7 | 1.86 | 0.18 |
Cued Recall | 18.7 ± 3.1 | 17.0 ± 4.1 | 3.43 | 0.07# |
MC Recognition | 30.0 ± 8.0 | 30.2 ± 7.1 | 0.004 | 0.95 |
Note.
Marginal significance.
COWAT= Controlled Oral Word Association Test; BDS-2= Behavioral Dyscontrol Scale 2nd edition; CVLT= California Verbal Learning Test, SD FR= Short-delay free recall, SD CR= Short-delay cued recall, LD FR= Long-delay free recall, LD CR= Long-delay cued recall; MC= Multiple-choice.