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. 2013 Sep 5;41(22):10476–10487. doi: 10.1093/nar/gkt799

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Schematic diagram and local structures of the native and modified U•U pairs in overhang regions (or duplex junctions). (A) Schematic diagram of the RNA duplex with five strands, the nicks, ^SeU•U pairs and normal Watson–Crick C-G pairs. (B) Superimposition comparison of ^SeU14•U1 (in red) with native U14•U1 pair (in cyan); the numbers represent the H-bond lengths (Å). (C) The stacking of two ^SeU•U pairs with the distance (3.11 Å) between the two neighbor Se atoms in the modified U14 and U2. (D) The stacking of two native U•U pairs with the distance (3.29 Å) between the two neighbor O atoms in native U14 and U2. The 2Fo-Fc maps of Se-4 and O-4 are showed.