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. 2013 Sep 9;41(22):10157–10169. doi: 10.1093/nar/gkt812

Figure 5.

Figure 5.

p18CycE expression prevents DNA-PKcs autophoshorylation. Confocal immunostaining for T2609-DNA-PKcs phosphorylation following irradiation in parental and p18CycE-expressing (A) HEK 293T and (B) C4-2 cells. (C) Confocal immunostaining of S2056 phosphorylation of DNA-PKcs following radiation in HEK 293T and p18CycE-expressing cells. (D) Graphical representation of the number of foci per cell at the indicated time for the two DNA-PKcs phosphorylation sites in HEK 293T parental and p18CycE-expressing cells. Error bars represent SD (n = 3).