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. 2013 Sep 2;41(22):10110–10123. doi: 10.1093/nar/gkt778

Figure 3.

Figure 3.

CPT exerts its effects at bidirectional promoters. (A) Analysis with WashU Epigenome Browser tools of the promoter region of the CPT-increased 256 antisense transcripts identified by Cufflinks. Shown chromatin features are respectively RNA Pol II density, H3K4me3 density, H3K27ac density and GC percentage in a region from 1000 bases upstream to 1000 bases downstream the TSS (dotted line). (B) Analysis with WashU Epigenome Browser tools of the promoter region of 249 randomly selected genes having FPKM between 1 and 100 and that did not demonstrate in our analysis a modification in antisense reads after CPT treatment.