Table 4.
Serum non-HDL cholesterol levels classified by drinking status and Mt5178 C/A genotype
| Drinking status | P for trend | |||
|---|---|---|---|---|
| |
Non- or ex-drinkers |
Occasional drinkers |
Daily drinkers |
|
| Mt5178C |
N = 44 |
N = 84 |
N = 111 |
|
| non-HDL cholesterol |
159.8 ± 5.4 |
146.2 ± 3.9 |
146.7 ± 3.4 |
P = 0.088 |
| non-HDL cholesterol† |
161.8 ± 5.4 |
145.7 ± 3.9* |
146.3 ± 3.4* |
P = 0.043 |
| non-HDL cholesterol‡ |
164.5 ± 6.7 |
148.0 ± 5.5* |
148.4 ± 4.6* |
P = 0.040 |
| Mt5178A |
N = 21 |
N = 60 |
N = 74 |
|
| non-HDL cholesterol |
151.2 ± 7.6 |
147.9 ± 4.5 |
142.6 ± 4.0 |
P = 0.245 |
| non-HDL cholesterol† |
153.7 ± 7.4 |
147.6 ± 4.3 |
142.1 ± 3.9 |
P = 0.140 |
| non-HDL cholesterol‡ | 159.7 ± 8.3 | 152.3 ± 5.7 | 147.3 ± 5.3 | P = 0.114 |
†non-HDL cholesterol levels are given as least-square mean ± SE adjusted for age and body mass index; ‡non-HDL cholesterol levels are given as least-square mean ± SE adjusted for age, body mass index, cigarette smoking, coffee consumption and antihypertensive medication use. Bonferroni correction for multiple comparisons was applied. *P < 0.05 vs non- or ex-drinkers. HDL, high-density lipoprotein; Mt5178C, mitochondrial DNA 5178 cytosine; Mt5178A, mitochondrial DNA 5178 adenosine.