TABLE 3.
Patient characteristics of women receiving breast cancer screening by breast MRI or mammography alone, 2005–2009.^
| Total | Women without prior breast cancer diagnosis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Breast MRI | Mammography only | Breast MRI | Mammography only | |||||||
| N | (%) | N | (%) | p-value | N | (%) | N | (%) | p-value | |
| Total | 2,831 | 1,288,924 | 1,559 | 1,228,812 | ||||||
| Age group | <0.0001 | <0.0001 | ||||||||
| <40 | 322 | (11.4) | 30,940 | (2.4) | 254 | (16.3) | 30,426 | (2.5) | ||
| 40–49 | 924 | (32.6) | 361,998 | (28.1) | 585 | (37.5) | 356,708 | (29.0) | ||
| 50–59 | 968 | (34.2) | 435,526 | (33.8) | 490 | (31.4) | 419,104 | (34.1) | ||
| 60–69 | 501 | (17.7) | 296,764 | (23.0) | 195 | (12.5) | 276,086 | (22.1) | ||
| 70–79 | 116 | (4.1) | 163,696 | (12.7) | 35 | (2.2) | 146,488 | (11.9) | ||
| Race/ethnicity | <0.0001 | <0.0001 | ||||||||
| White, non-Hispanic | 2,347 | (85.3) | 936,313 | (75.0) | 1,293 | (85.9) | 888,808 | (74.7) | ||
| Black, non-Hispanic | 32 | (1.2) | 33,534 | (2.7) | 19 | (1.3) | 32,222 | (2.7) | ||
| Hispanic | 95 | (3.5) | 68,360 | (5.5) | 62 | (4.1) | 66,199 | (5.6) | ||
| Asian | 189 | (6.9) | 174,915 | (14.0) | 79 | (5.2) | 169,077 | (14.2) | ||
| Other* | 89 | (3.2) | 35,414 | (2.8) | 52 | (3.5) | 33,860 | (2.8) | ||
| Missing | 79 | 40,388 | 54 | 38,646 | ||||||
| Age at menarche | 0.18 | 0.85 | ||||||||
| <11 | 525 | (29.2) | 237,428 | (29.4) | 280 | (28.6) | 229,361 | (29.3) | ||
| 12–13 | 851 | (47.3) | 374,563 | (45.4) | 444 | (45.4) | 355,300 | (45.3) | ||
| ≥14 | 424 | (23.6) | 208,205 | (25.2) | 255 | (26.0) | 198,854 | (25.4) | ||
| Missing | 1,031 | 463,728 | 580 | 445,297 | ||||||
| Age at first birth | <0.0001 | <0.0001 | ||||||||
| Nulliparous | 656 | (33.4) | 237,681 | (25.6) | 337 | (32.9) | 227,018 | (25.7) | ||
| <20 | 144 | (7.3) | 139,005 | (14.9) | 76 | (7.4) | 131,818 | (14.9) | ||
| 20–24 | 309 | (15.7) | 217,071 | (23.3) | 157 | (15.3) | 204,374 | (23.1) | ||
| 25–29 | 347 | (17.7) | 138,948 | (14.9) | 181 | (17.7) | 131,450 | (14.9) | ||
| >30 | 510 | (25.9) | 197,379 | (21.2) | 272 | (26.6) | 189,081 | (21.4) | ||
| Missing | 865 | 358,840 | 536 | 345,071 | ||||||
| Mammography in prior 12 months | ||||||||||
| No | 449 | (15.9) | 237 | (15.2) | ||||||
| Yes | 2,382 | (84.1) | 1,322 | (84.8) | ||||||
| Personal history of breast cancer | ||||||||||
| No | 1,559 | (55.1) | 1,228,812 | (95.3) | <0.0001 | |||||
| Yes | 1,272 | (44.9) | 60,112 | (4.7) | ||||||
| First degree family history of breast cancer1 | <0.0001 | <0.0001 | ||||||||
| No | 1,078 | (47.8) | 953,510 | (82.6) | 376 | (29.6) | 912,974 | (83.0) | ||
| Yes | 1,177 | (52.2) | 201,325 | (17.4) | 895 | (70.4) | 187,641 | (17.0) | ||
| Missing | 576 | 134,089 | 288 | 128,197 | ||||||
| “Missing” for MRI mainly due to no self-reported patient information | ||||||||||
| Prior breast biopsy (not benign only, includes FNA) | <0.0001 | <0.0001 | ||||||||
| No | 906 | (32.0) | 984,808 | (76.4) | 1,017 | (65.2) | 981,500 | (79.9) | ||
| Yes | 1,925 | (68.0) | 304,116 | (23.6) | 542 | (34.8) | 247,312 | (20.1) | ||
| BI-RADS breast density1,2 | <0.0001 | <0.0001 | ||||||||
| Fatty | 90 | (5.0) | 106,888 | (11.5) | 66 | (5.9) | 101,453 | (11.5) | ||
| Scattered | 505 | (28.3) | 369,748 | (39.9) | 315 | (28.1) | 350,640 | (39.7) | ||
| Heterogeneous | 795 | (44.6) | 359,743 | (38.9) | 470 | (41.9) | 343,443 | (38.9) | ||
| Extremely dense | 394 | (22.1) | 89,247 | (9.6) | 271 | (24.2) | 86,759 | (9.8) | ||
| Missing | 1,047 | 363,298 | 437 | 346,517 | ||||||
| Combinations of risk factors | ||||||||||
| Positive family history and extreme breast density | ||||||||||
| 204 | (12.9) | 14,449 | (1.7) | <0.0001 | 166 | (16.8) | 13,927 | (1.7) | <0.0001 | |
| Prior breast biopsy and positive family history | ||||||||||
| 693 | (30.7) | 62,897 | (5.4) | <0.0001 | 415 | (32.7) | 49,739 | (4.5) | <0.0001 | |
| Prior breast biopsy and extreme breast density | ||||||||||
| 262 | (14.7) | 23,917 | (2.6) | <0.0001 | 141 | (12.6) | 21,544 | (2.4) | <0.0001 | |
| Positive family history, extreme breast density and prior breast biopsy | ||||||||||
| 122 | (7.7) | 4,834 | (0.6) | <0.0001 | 85 | (8.6) | 4,329 | (0.5) | <0.0001 | |
^
Restricted facilities are those with 90% or higher data capture of MRI exams.
*
Other race/ethnicity includes Native Hawaiian or other Pacific Islander, American Indian or Alaskan Native, mixed (>1) race, as well as race reported as other.
1
Missing information at time of MRI exam was filled in using information from the most recent mammogram in the prior 12 months.
2
Breast density was not collected at time of MRI. Missing data on breast density was filled in for both MRI and mammography from a mammogram within +/− 18 months if no change in hormone therapy use and no breast cancer diagnosis was noted.