Table 5.
Relative odds of lower than median values of quality of life scores at baseline by categories of tangible social support, by cancer stage in the Pathways study (N=3,139)
| High level of tangible support |
Medium level of tangible support |
Low level of tangible support |
p-value | p-interaction | |
|---|---|---|---|---|---|
| Range | 19-20 | 16-18 | 4-15 | ||
| Early stage†, N | 1,021 | 677 | 742 | ||
| Fact-B | 1.00 | 1.17 | 1.28 | 0.11 | |
| 95% CI | (0.92-1.49) | (0.97-1.69) | |||
| Fact-G | 1.00 | 1.17 | 1.30 | 0.04 | |
| 95% CI | (0.92-1.48) | (0.99-1.71) | |||
| TOI-PFB | 1.00 | 1.43 | 1.18 | 0.26 | |
| 95% CI | (1.13-1.82) | (0.90-1.56) | |||
| BCS | 1.00 | 0.93 | 0.87 | 0.58 | |
| 95% CI | (0.74-1.17) | (0.67-1.14) | |||
| PWB | 1.00 | 1.39 | 1.23 | 0.17 | |
| 95% CI | (1.10-1.75) | (0.94-1.60) | |||
| Late stage†, N | 149 | 96 | 87 | ||
| Fact-B | 1.00 | 1.74 | 2.47 | 0.03 | 0.07 |
| 95% CI | (0.87-3.50) | (1.03-5.94) | |||
| Fact-G | 1.00 | 1.57 | 2.75 | 0.03 | 0.07 |
| 95% CI | (0.78-3.15) | (1.12-6.77) | |||
| TOI-PFB | 1.00 | 1.94 | 2.33 | 0.14 | 0.11 |
| 95% CI | (0.96-3.94) | (0.96-5.68) | |||
| BCS | 1.00 | 2.52 | 2.47 | 0.01 | 0.007 |
| 95% CI | (1.25-5.08) | (1.06-5.78) | |||
| PWB | 1.00 | 1.99 | 1.70 | 0.11 | 0.07 |
| 95% CI | (0.98-4.06) | (0.74-4.00) |
p-value, continuous variable,
p-interaction=p-value, test for interaction
Early stage includes in situ, localized, and regional with lymph nodes only. Late stage cancer includes regional, distant, metastases or systemic.
FACT-B=Functional Assessment Cancer Therapy-Breast; FACT-G=Functional Assessment Cancer Therapy-General; TOI-PFB=Trial Outcome Index-Physical/Functional/Breast; BCS=breast cancer symptoms; PWB=physical well-being
Multivariate-adjusted models adjusted for age (continuous), time between diagnosis and study entry, race/ethnicity (White (ref), African-American, Hispanic, Asian, other), education (<HS, HS, <college, college degree or greater), income (<$25K, $25-<$70K, $70K+(ref)), stage (I (ref), II, III, IV), estrogen receptor status (positive, negative (ref)), nodal status (positive, negative (ref)), surgery type (mastectomy (ref), lumpectomy, other), chemotherapy (yes, no (ref)), hormonal treatment (yes, no (ref)), radiation (yes, no (ref)), menopausal status (postmenopausal, premenopausal (ref)), parity (0, 1-2, 3 or more), comorbidity (any comorbidity defined by Charlson index, no (ref)), body mass index (BMI<25 (ref), 25-<30, 30+ kg/m2), smoking (never (ref), past, current), physical activity (quartiles, Q1=ref), social networks, and social support mechanisms.