Table 3. Hazard ratios for prostate cancer in the IMPACT study, (Cox regression analyses) and for breast cancer in the RMH study, (weighted retrospective Cox regression analyses), by BRCA1/2 mutation status.

Cohort	Genetic status	Number with cancer	Number without cancer	HR	95% CI	P
IMPACT set	BRCA1 mutation carriers	5	235	1.00	0.085–11.7	0.999
	BRCA2 mutation carriers	16	191	0.493	0.103–2.36	0.376
	All mutation carriers	21	426	0.658	0.188–2.30	0.512
RMH Carrier Clinic Set	BRCA1 mutation carriers	66	65	1.063	0.448–2.53	0.889
	BRCA2 mutation carriers	60	50	0.467	0.209–1.04	0.063
	All mutation carriers	126	115	0.782	0.449–1.36	0.384