Table 1. Demographic and clinical characteristics of patients.

Characteristics at diagnosis	No. of patients (%)
Age, median (range, years)	35 (15–77)
Male gender	68 (58.6%)
Histologic subtype
Nodular sclerosis	78 (67.2%)
Mixed cellularity	22 (19%)
Lymphocyte-rich	5 (4.3%)
Lymphocyte-depleted	3 (2.6%)
Not classifiable	8 (6.9%)
Ann Arbor stage
I	21 (18.1%)
II	41 (35.3%)
III	27 (23.3%)
IV	27 (23.3%)
Stage (limited vs. advanced)
Limited	45 (38.8%)
Advanced	71 (61.2%)
B symptoms present	37 (31.9%)
International Prognostic Score ≥3 (high-risk)	45 (38.8%)
EBER positivity	43 (37.1%)
Primary treatment
Chemotherapy	85 (73.3%)
Chemoradiotherapy	31 (26.7%)

EBER, Epstein-Barr virus-encoded RNA-1 and RNA-2 assessed by in situ hybridization.