Table 4. Multivariate analysis for overall survival (OS) and event-free survival (EFS).

		OS			EFS
Covariate	Subcategory	HR	95% CI	P-value	HR	95% CI	P-value
IPS	<3 vs. ≥3	2.665	1.03–6.83	0.041	1.374	0.74–2.52	0.307
CD68expression	(−) vs. (+)	2.452	0.96–6.25	0.06	2.391	1.27–4.84	0.007
IPS	<3 vs. ≥3	2.160	0.79–5.88	0.132	1.257	0.65–2.42	0.496
CD163expression	(−) vs. (+)	3.009	1.14–7.92	0.026	2.148	1.05–4.36	0.034

HR, hazard ratio; CI, confidence interval; IPS, international prognostic score.