Table 3. Simple clinical indices assessed in the studies and their association with survival to discharge.
| Number of observations | All | Survived n = 1405 | Died n = 396 | P | ||
| Temperature | °C | 1794 | 38 (37.2–39) | 38 (37.2–39) | 37.8 (37–38.9) | 0.01 |
| Shock | number (%) | 1800 | 186 (10.3) | 127 (9) | 59 (15) | 0.001 |
| MAP | mmHg | 1786 | 77.4 (69.3–87.4) | 76.7 (69.3–86.7) | 79.2 (69.3–90) | 0.02 |
| Heart Rate | beats/minute | 739 a | 105 (96–120) | 104 (95–120) | 110 (104–124) | 0.007 |
| Oxygen saturation | % | 185 b | 96 (94–98) | 96 (94–98) | 95 (92–97) | 0.01 |
| Respiratory Rate | breaths/minute | 1796 | 28 (22–32) | 26 (22–32) | 30 (24–36) | 0.0001 |
| GCS | 1800 | 10 (8–15) | 12 (8–15) | 8 (6–11) | 0.0001 | |
| RCAM score | 1795 | 2 (1–3) | 2 (1–3) | 3 (2–3) | 0.0001 | |
| Abnormal glucose | number (%) | 1769 | 400 (22.6) | 266 (19.3) | 134 (34.6) | <0.0001 |
| Oligo-anuric | number (%) | 1638 c | 257 (15.7) | 155 (11.9) | 102 (30.9) | <0.0001 |
All numbers represent median (interquartile range) except where stated.
a
Heart rate was not recorded in SEAQUAMAT;
b
Oxygen saturation was only measured in the two smaller studies;
c
Oligo-anuria was not recorded in the Bangladeshi study. MAP: Mean arterial pressure; mmHg: millimetres of mercury; GCS: Glasgow Coma Score; RCAM: Respiratory Coma Acidosis Malaria score;