|
Inflammation-related
|
| Kallikrein 1- related peptidase |
Down-regulated in BM SOUP-treated NOD mice |
Up-regulated in salivary glands of IQI/Jic mice |
[52]
|
| Calreticulin/Calmodulin |
Down-regulated in BM SOUP-treated NOD mice |
Up-regulated in salivary glands of IQI/Jic mice |
[24], [25]
|
|
SS biomarker
|
| Sjogrens syndrome antigen B |
Down-regulated in BM SOUP-treated NOD mice |
Up-regulated in SS patients |
[9], [63]
|
|
Salivary gland biology
|
| α-Amylase |
Up-regulated in BM SOUP-treated NOD mice |
Down-regulated in SS patients |
[36]–[39]
|
| Aquaporin-1 |
Up-regulated in BM SOUP-treated NOD mice |
Down-regulated in SS patients |
[40], [41], [43]
|
| Aquaporin-5 |
Up-regulated in BM SOUP-treated NOD mice |
Down-regulated in SS patients |
[40], [41], [43]
|
| Parotid secretory protein |
Up-regulated in BM SOUP-treated NOD mice |
Down-regulated in SS patients |
[44], [45]
|
|
Stem cell and development
|
| Nestin |
Up-regulated in BM SOUP-treated NOD mice |
Up-regulated in repaired lacrimal glands |
[47], [64]
|
| Vimentin |
Up-regulated in BM SOUP-treated NOD mice |
Up-regulated in repaired lacrimal glands |
[47], [64]
|
|
Apoptosis
|
| CASP8-associated protein 2 |
Down-regulated in BM SOUP-treated NOD mice |
Up-regulated in SS |
[49], [65]
|
| Caspase-8 |
Down-regulated in BM SOUP-treated NOD mice |
– |
– |
| Caspase recruitment domainprotein 12 |
Down-regulated in BM SOUP-treated NOD mice |
– |
– |
