Table 1. Baseline characteristics of Non-alcoholic fatty liver disease (NAFLD) and Non-alcoholic steatohepatitis (NASH) patients and controls.
| Patients | Controls | Patients vs. Controls | NASH vs. NAFLD | |||
| all | NAFLD | NASH | ||||
| Age (years) | 48.9±2.0 | 48.6±2.7 | 49.1±2.7 | 35.9±1.9 | p<0.0001 | ns |
| Weight (kg) | 85.7±2.1 | 82.9±2.9 | 87.0±2.8 | 71.0±1.1 | p<0.0001 | ns |
| BMI (kg/m2) | 29.1±0.6 | 28.5±1.0 | 29.3±0.8 | 22.7±0.2 | p<0.0001 | ns |
| Fasting glucose (mmol/l) | 5.0±0.1 | 5.0±0.1 | 5.0±0.1 | 5.2±0.1 | p = 0.0071 | ns |
| Fasting insulin (mU/l) | 38.9±3.1 | 27.8±2.3 | 43.9±4.1 | 14.9±0.9 | p<0.0001 | p = 0.0033 |
| HOMA2-IR | 4.7±0.3 | 3.5±0.3 | 5.2±0.4 | 1.9±0.1 | p<0.0001 | p = 0.0044 |
| Fasting glucagon (pg/ml) | 52.0±6.1 | 42.9±10.5 | 56.1±7.5 | 25.8±1.7 | p<0.001 | ns |
| ASAT (U/l) | 44.6±4.4 | 30.6±2.6 | 50.9±6.0 | 26.8±1.1 | p = 0.0001 | p = 0.0044 |
| ALAT (U/l) | 61.5±6.6 | 46.3±5.9 | 68.3±9.0 | 21.8±1.3 | p<0.0001 | ns |
| GGT (U/l) | 82.5 ±10.3 | 66.7±9.2 | 89.6±14.3 | 22.8±2.8 | p<0.0001 | ns |
Data are expressed as mean±SEM. n = 52 patients (NAFLD n = 16 (30.8%), NASH n = 36 (69.2%)); n = 50 controls. Differences in baseline characteristics of patients vs. controls and NAFLD vs. NASH are expressed as p-values (Mann-Whitney U test). P≤0.05, statistically significant difference; ns, not significant.