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. 2014 Jan 29;9(1):e87561. doi: 10.1371/journal.pone.0087561

Figure 2. Sodium ferulate attenuates Ang II-induced oxidative stress in VSMCs.

Figure 2

After synchronization, VSMCs were stimulated with 1 µmol/L Ang II for 1 hour, with or without sodium ferulate at a dose of 200 µmol/L. (A) Intracellular ROS generation was detected using DCFH-DA probe (× 100 magnifications). NAPDH oxidase (B) and SOD activity (C) were analyzed using ELISA kits. Protein levels of p-p38 and p-ERK1/2 (D) were examined by western blot. N = 3 for each group, * P<0.05 vs. the control group, * * P<0.05 vs. the Ang II group.