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. 2014 Jan 29;9(1):e87857. doi: 10.1371/journal.pone.0087857

Table 1. Baseline characteristics of 165 (68 female) patients with idiopathic chronic glomerulonephritis divided according to the urine MCP-1 concentrations (low <0.05 mg/mmol and high >0.05 mg/mmol).

Variables Low MCP-1 High MCP-1 P-value
Gender (M/F) 79 (55/24) 86 (42/44)
Age (years) 48.0 (33.0–55.0) 50.0 (31.8–66.0) 0.26
Follow-up (years) 9.4 (5.9–10.5) 6.4 (3.9–8.9) 0.001*
MAP (mm Hg) 100.0 (93.3–110.0) 106.7 (94.2–116.5) 0.06
S. creatinine (µmol/L) 85.5 (72.0–112.3) 93.0 (73.5–115.0) 0.24
GFR (ml/min/1.73) 72.4 (54.7–92.6) 63.0 (46.4–83.8) 0.02*
S. albumin (g/L) 34.0 (28.0–40.0) 29.0 (19.0–34.0) <0.001*
IgG-uria (mg/mmol) 3.8 (1.1–7.3) 7.8 (2.7–24.2) <0.001*
HC-uria (mg/mmol) 0.82 (0.5–1.6) 1.9 (0.7–4.3) 0.001*
ACR (mg/mmol) 53.7 (7.2–150.9) 161.9 (58.6–475.7) <0.001*

Data are presented as median and inter-quartile range (in parentheses).

MAP =  mean arterial blood pressure; GFR =  glomerular filtration rate; ACR =  urine albumin/creatinine ratio; HC-uria  =  urine alpha-1 microglobulin/creatinine ratio.

*

The difference between the groups is statistically significant.