Table 1. Baseline characteristics of 165 (68 female) patients with idiopathic chronic glomerulonephritis divided according to the urine MCP-1 concentrations (low <0.05 mg/mmol and high >0.05 mg/mmol).
Variables | Low MCP-1 | High MCP-1 | P-value |
Gender (M/F) | 79 (55/24) | 86 (42/44) | |
Age (years) | 48.0 (33.0–55.0) | 50.0 (31.8–66.0) | 0.26 |
Follow-up (years) | 9.4 (5.9–10.5) | 6.4 (3.9–8.9) | 0.001* |
MAP (mm Hg) | 100.0 (93.3–110.0) | 106.7 (94.2–116.5) | 0.06 |
S. creatinine (µmol/L) | 85.5 (72.0–112.3) | 93.0 (73.5–115.0) | 0.24 |
GFR (ml/min/1.73) | 72.4 (54.7–92.6) | 63.0 (46.4–83.8) | 0.02* |
S. albumin (g/L) | 34.0 (28.0–40.0) | 29.0 (19.0–34.0) | <0.001* |
IgG-uria (mg/mmol) | 3.8 (1.1–7.3) | 7.8 (2.7–24.2) | <0.001* |
HC-uria (mg/mmol) | 0.82 (0.5–1.6) | 1.9 (0.7–4.3) | 0.001* |
ACR (mg/mmol) | 53.7 (7.2–150.9) | 161.9 (58.6–475.7) | <0.001* |
Data are presented as median and inter-quartile range (in parentheses).
MAP = mean arterial blood pressure; GFR = glomerular filtration rate; ACR = urine albumin/creatinine ratio; HC-uria = urine alpha-1 microglobulin/creatinine ratio.
The difference between the groups is statistically significant.