Table 1. Summary of similarities between insect hemocytes and human neutrophils.
| Hemocytes | Neutrophils | |
|---|---|---|
| Phagocytosis | Lectin-mediated | Lectin-mediated |
| ROS | O2−, H2O2, NO− | O2−, H2O2, NO− |
| Degranulation | Yes | Yes |
| AMPs | Peroxynectin, transferrin, lysozyme, defensin | MPO, transferrin, lysozyme, defensin |
| Receptors | TLRs, B-1,3-glucan, IL-IR | TLRs, B-1,3-glucan, IL-IR |
| Transcription factors | NFκB, IκB | NFκB, IκB |
| Cascades | IMD, JNK, JAK-STAT | IMD, JNK, JAK-STAT |
| Kinases | p38 MAPK, ERK, PKC, PKA | p38 MAPK, ERK, PKC, PKA |
| Neutrophil extracellular nets (NET) | NET-like structures present | NETs present |