Table 1. Summary of baseline and outcome data from one-month trial of oral M. vaccae.
| Arms | No. | Sex F/M |
Age | Dx | Sputum smear (+/−) |
Axillary temperature (Co) |
Body weight (kg) |
BMI (kg/m2) |
Hemoglobin (g/L) |
ESR (mm/h) |
Leukocytes (x109L) |
Lymphocytes (%) |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| before | after | before | after | before | after | before | after | before | after | before | after | before | after | before | after | ||||||||
| M. vaccae | 22 | 7/15 | 41.9 ± 10 (39) |
1stDx = 5 RTB = 4 MDR = 13 |
22/0 | 15/7 | 37.1 ± 0.5 |
36.8 ± 0.5 |
55.9 ± 9.8 |
56.5 ± 9.4 |
19.3 ± 2.6 |
19.5 ± 2.6 |
128.4 ± 17.7 |
127.4 ± 13.5 |
18.5 ± 14.1 |
18.3 ± 11.6 |
8.5 ± 2.6 |
7.9 ± 2.2 |
27.9 ± 7.7 |
30.9 ± 6.2 |
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| 31.8% converted p = 0.03 |
-0.3 p = 0.05 |
+0.6 p = 0.004 |
+0.2 p = 0.003 |
-1 p = 0.59 |
-0.2 p = 0.92 |
-0.6 p = 0.15 |
+3 p = 0.006 |
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| Placebo | 21 | 4/17 | 44.3 ± 11 (44) |
1stDx = 3 RTB = 2 MDR = 16 |
21/0 | 19/2 | 37.4 ± 0.6 |
37.2 ± 0.7 |
63.9 ± 12.6 |
63.8 ± 12.9 |
22.01 ± 4.8 |
21.99 ± 4.9 |
105 ± 18.8 |
106.2 ± 18.7 |
22.4 ± 12.3 |
18.6 ± 8.9 |
7.5 ± 3.5 |
7.5 ± 2.8 |
27.2 ± 8.6 |
27.1 ± 5.5 |
|||
| 9.5% converted p = 0.83 |
-0.2 p = 0.12 |
-0.1 p = 0.77 |
-0.02 p = 0.65 |
+1.2 p = 0.26 |
-3.8 p = 0.001 |
0 p = 0.98 |
-0.1 p = 0.93 |
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| Difference between arms (P) |
0.27 | 0.65 | 0.14 | 1.0 | 0.07 | 0.08 | 0.12 | 0.03 | 0.04 | 0.03 | 0.04 | 0.001 | 0.001 | 0.34 | 0.92 | 0.29 | 0.6 | 0.78 | 0.04 | ||||