Table 4. Nasal HI and neutralizing antibody responses after two doses of the nasal vaccine.
| Week | HI titers a | NT titers a | |
|---|---|---|---|
| GMT (Mean geometric increase) | 0 | 12.4 (1.00) | 15.4 (1.00) |
| 6 | 38.8 (3.13) | 90.5 (5.88) |
a Nasal HI and neutralization titers were determined using concentrated nasal wash samples containing 1 mg/ml total protein. Nasal HI and neutralization titers of <1:20 were considered negative and were arbitrarily assigned a titer of 1:10.