Table 6. Cross-reactive HI and neutralizing antibody responses to A/Sydney virus after two doses of the A/Victoria vaccine.
| Item | Antibody responses | Week | Seruma | Nasal washb |
|---|---|---|---|---|
| GMT (Mean geometric increase) | HI antibody | 0 | 21.2 (1.00) | 13.6 (1.00) |
| 6 | 30.5 (1.44) | 22.2 (1.63) | ||
| Neutralizing antibody | 0 | 160.0 (1.00) | 23.0 (1.00) | |
| 6 | 233.2 (1.46) | 48.7 (2.12) |
a Serum HI and neutralization titers of < 1:10 were considered negative and arbitrarily assigned a titer of 1:5. b Nasal wash HI and neutralization titers were determined using concentrated nasal wash samples containing 1 mg/ml total protein. Nasal HI and neutralization titers of < 1:20 were considered negative and arbitrarily assigned a titer of 1:10.