Table 1. TcdA mAb 5D8 and 2C7 lg gene germline and CDR3 analysis.

Heavy Chain
mAb	VH family	VH mutation	D region	JH	JH mutation	CDR3 aa seq
5D8	1–4*01	6%	1–1*01	3*01	7%	CARIGDYYVSFAFW
2C7	9–2-1*01	5%	2–3*01	3*01 or 3*02	23%	CAAIHDENW
Kappa chain
mAb	VK family	VK mutation		JK	JK mutation	CDR3 aa seq
5D8	6–17*01	2%		5*01	3%	CQQHFGTPLTF
2C7	3–2*01	2%		1*01	0	CQQTKEVPRTF