Table 1. Yields of process development (10L) fermentations performed by NTC and VGXI and scaled up cGMP fermentations performed by VGXI.

Fermentation scale	Plasmid	Final cell density (OD600)	Plasmid volumetric yield (mg/L)	Plasmid specific yield (mg/L/OD600)
NTC—10L (Fig. 2B)	NTC8485-O2-gD2	111	1700	15.3
VGXI—10L (Fig. 2C)	NTC8485-O2-gD2	92	1530	16.7
VGXI—320L (cGMP; Fig. 2D)	NTC8485-O2-gD2	85	1830	21.6
VGXI—320L (cGMP)	NTC8485-O2-UgD2tr	83	1270	15.4