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. 2013 Sep 25;44(2):146–153. doi: 10.3109/00498254.2013.836257

Figure 3.

Figure 3.

Expression of functional liver markers in reconstituted livers from TK-NOG mice. Hepatocyte-like colonies in a TK-NOG mouse liver that was transplanted with differentiation D21 HepaRG® cells (upper panel) and human hepatocyte colonies in a TK-NOG mouse liver that was transplanted with cryopreserved human hepatocytes (HEP187170; 26 years, female) (lower panel) were assessed for functionality by histochemical and immunohistochemical analyses. Serial liver sections were stained for H&E, PAS, CYP3A4 and MRP2. Bar = 100 μm.