Figure 3.

Under short-term CD4 depletion and P. murina infection, the influx of pulmonary inflammatory cells differs distinctly between BALB-STD mice (which develop PH) and IFN-γ–STD mice (which do not develop PH). Cell types counted included total lung cells; macrophages (Macs), polymorphonuclear cells (PMN), eosinophils (EOS), natural killer (NK) cells, and γδ T cells as percentage in BALF; and B cells, CD4⁺ T cells, CD8⁺ T cells, and CD4⁺CD8⁺ cells. Important differences are described in the Results section. Data are representative of three independent experiments and are expressed as means ± SEM. n = 5. ^∗P ≤ 0.05, ^∗∗P ≤ 0.01, ^∗∗∗P ≤ 0.001, and ^∗∗∗∗P ≤ 0.0001 versus control.