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. 2014 Jan 30;8:12. doi: 10.3389/fncel.2014.00012

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Copyright © 2014 Goudriaan, Camargo, Carney, Oliet, Smit and Verheijen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Microarray analysis of strongest regulated neuron-responsive astrocyte genes. Shown are 36 of the most up – and down-regulated transcripts in astrocytes when co-cultured with neurons, which were subsequent removed by cold jet treatment (CC-CJ), compared to astrocytes cultured alone (AA-CJ). Each individual gene expression level was normalized (see methods) and plotted on a Log2 scale with red representing increased and green decreased mRNA levels in CC-CJ astrocytes compared to astrocytes cultured alone (AA-CJ).