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Modified Goldman Scores for Study Cohort
| Modified Goldman Score |
Total No. With Mutation /Total No. of Pedigrees (N=47/306) |
Detection Rate, %a | Distribution of Mutation-Positive Cases, % (n=47) |
|---|---|---|---|
| 1 | 8/9 | 88.9 | 17.0 |
| 2 | 24/59 | 40.7 | 51.1 |
| 3 | 4/10 | 40.0 | 8.5 |
| 3.5 | 4/40 | 10 | 8.5 |
| 4 | 7/188 | 3.7 | 14.9 |
Fisher exact P values comparing categories in Goldman-modified criteria: 1 vs 2: P = .01; 2 vs 3:P > .99; 3 vs 3.5: P = .04; and 3.5 vs 4: P = .11.
