Table 1.
Responding-related behaviors across the microinjection period during non-experimental days.
| Response latency (s)2 | Press rate (#/min) | Press time (min) | |
|---|---|---|---|
| Week 1 | 54.3 ± 21.9 | 20.4 ± 6.6 | 4.3 ± 1.9 |
| Week 21 | 53.8 ± 14.1 | 21.0 ± 7.0 | 3.9 ± 1.2 |
| Week 3 | 40.5 ± 6.3 | 24.4 ± 10.0 | 3.4 ± 1.3 |
| Week 4 | 47.8 ± 12.5 | 18.7 ± 5.3 | 3.5 ± 1.2 |
| Week 5 | 76.9 ± 19.7 | 24.2 ± 5.7 | 2.6 ± 0.9 |
| Week 6 | 66.8 ± 9.6 | 30.4 ± 7.1 | 2.3 ± 0.8 |
| Week 7 | 46.7 ± 16.3 | 25.5 ± 5.6 | 2.7 ± 1.1 |
1
0.02 μg α-methyl 5-HT was microinjected on weeks 2–3, 0.2 μg on weeks 4–5, and 2.0 μg on weeks 6–7. Values listed here represent pressing during non-injection days. Repeated measures ANOVA did not identify any significant effect of week across the parameters listed.
2
Mean weekly values were calculated using data from Monday, Tuesday, and Friday from the week just after surgery and on injection weeks (see Materials and Methods). Values are reported as mean ± SEM (n = 8).