Skip to main content
. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Cell Biochem. 2013 Feb;114(2):435–447. doi: 10.1002/jcb.24383

Figure 4. ET-1 attenuates shear-mediated increase in NO generation and H2O2 levels in pulmonary arterial endothelial cells.

Figure 4

PAEC were acutely exposed to shear stress (20 dyn/cm2, 4 h) in the presence or absence of ET-1 (100nM, 4h) and the media used for the detection of H2O2 and NOx. The shear mediated increase in NOx (A) and H2O2 (B) were attenuated in the presence of ET-1. Data are mean± SEM; n =6-12. *P <0.05 vs. no shear, †P <0.05 vs. shear alone, ‡P<0.05 vs. ET-1 alone.