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Severe toxicities on E2496 according to age.*
| Toxicity Type | Age ≥60 years (n=45) | Age <60 years (n=789) | ||||
|---|---|---|---|---|---|---|
| Grade^ | Grade^ | |||||
| 3 | 4 | 5 | 3 | 4 | 5 | |
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |
| Haematological | 11 (24) | 31 (69) | - | 372 (47) | 308 (39) | - |
| Non-Haematological | 14 (31) | 6 (13) | 4 (9) | 322 (41) | 53 (7) | 2 (<1) |
Grade 3, 4, and 5 adverse events (includes all patients who received any protocol treatment, regardless of eligibility status).
Worst degree.
