Table 2.
Total number of next-generation sequencing reads/fragments available for gastrointestinal cancers organized by cancer and tissue type
|
Cohort |
Statistics |
Primary tumor |
Primary tumor |
Blood |
Solid tissue |
|||
|---|---|---|---|---|---|---|---|---|
| RNA | DNA | Human genome coverage a | DNA | Human genome coverage a | DNA | Human genome coverage a | ||
| COAD |
Min |
5,244,743 |
60,872,080 |
0.47 |
64,637,478 |
0.50 |
148,341,394 |
1.18 |
| Mean |
26,127,635 |
205,217,167 |
1.63 |
182,959,915 |
1.45 |
224,838,391 |
1.77 |
|
| Median |
27,424,762 |
196,408,988 |
1.57 |
193,657,350 |
1.49 |
196,072,876 |
1.57 |
|
| Max |
64,021,517 |
1,162,469,344 |
9.43 |
354,790,740 |
2.85 |
429,443,164 |
3.36 |
|
| READ |
Min |
19,665,974 |
89,943,982 |
0.70 |
90,122,736 |
0.70 |
95,061,666 |
0.75 |
| Mean |
26,782,703 |
225,818,442 |
1.79 |
214,787,544 |
1.71 |
150,549,985 |
1.19 |
|
| Median |
27,121,702 |
227,226,239 |
1.81 |
224,045,358 |
1.80 |
159,027,517 |
1.26 |
|
| Max |
33,338,326 |
461,153,444 |
3.68 |
367,295,986 |
2.93 |
189,083,240 |
1.47 |
|
| STAD |
Min |
127,157,036 |
259,701,502 |
2.08 |
NA |
NA |
418,702,808 |
3.34 |
| Mean |
155,138,810 |
300,668,630 |
2.40 |
NA |
NA |
448,318,606 |
3.58 |
|
| Median |
155,490,548 |
280,015,346 |
2.23 |
NA |
NA |
448,318,606 |
3.58 |
|
| Max | 193,445,130 | 362,289,042 | 2.88 | NA | NA | 477,934,404 | 3.82 | |
Paired reads are counted as two single fragments. COAD, colon adenocarcinoma; READ, rectum adenocarcinoma; STAD, stomach adenocarcinoma; NA, no data available. aAverage coverage was calculated as the number of reads multiplied by the average read length (51 nt) and divided by the corresponding genome length, divided by two for diploid genome.