Table 5.
Counts of colorectal samples, positive (+) or negative (−) for identified viruses, in matched tumor/normal specimen pairs
Sample type |
Virus name |
Matched control DNA
N
= 111 2 (blood:solid) |
Adjusted
p
values for association |
|||
---|---|---|---|---|---|---|
Tumors vs. all controls | Tumors vs. blood | Tumors vs. solid tissue | ||||
Tumor DNA |
EBV |
+ |
− |
0.02 |
0.06 |
1 |
+ |
3 (3:0) |
21 (19:2) |
||||
− |
5 (5:0) |
82 (64:18) |
||||
CMV |
+ |
− |
0.03 |
0.06 |
1 |
|
+ |
0 |
12 (11:1) |
||||
− |
1 (1:0) |
98 (79:19) |
||||
HHV-6B |
+ |
− |
1 |
0.98 |
0.07 |
|
+ |
4 (1:3) |
8 (8:0) |
||||
− |
10 (2:8) |
89 (80:9) |
||||
HPV-18 |
+ |
− |
- |
- |
- |
|
+ |
0 |
0 |
||||
− | 0 | 0 |
N, number of matched pairs. blood: solid, counts for the non-malignant samples by tissue type: whole blood and solid adjacent tissue, respectively.