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. 2013 Aug 2;125(Pt 12):575–585. doi: 10.1042/CS20130105

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© 2013 The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Licence (CC-BY)(http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

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(A, B) Representative immunohistochemical MMP-11 staining of skin wound samples from diabetic (db⁺/db⁺) mice treated with vehicle (6 μl of 0.9% NaCl/mouse per day) or RLX (25 μg/mouse per day, subcutaneously) at day 12. Arrows indicate staining positivity. (C) Quantification of MMP-11 staining per field in normoglycaemic (db^+/+m) and diabetic (db⁺/db⁺) mice treated with vehicle (6 μl of 0.9% NaCl/mouse per day) or with RLX (25 μg/mouse per day, subcutaneously) at day 12. Each bar represents the mean±S.D. of six animals. *P<0.05 compared with db^+/+m+vehicle; ^#P<0.01 compared with db⁺/db⁺+vehicle.