Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Dec 5;10:146. doi: 10.1186/1742-2094-10-146

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Bachstetter et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

PLP-ISEdel mice show motor impairments in the open field task. Mice were placed in an open field maze for 30 minutes and their activity was recorded and analyzed using video tracking software. A significant impairment was found in total distanced traveled (A), and velocity of movement (B). In the 4-month-old group, an age-related difference in thigmotaxis behavior between the wild-type (WT) and PLP-ISEdel mice was found (C), which is shown in a computer-generated trace of the animal’s movements over 30 minutes (D). (2-month-old WT (n = 15) versus PLP (n = 16); 4-month-old WT (n = 12) versus PLP (n = 12).