Table 5.
RESULTS OF MULTIPLE LOGISTIC REGRESSION ANALYSES
| A: CHARACTERISTICS INDEPENDENTLY ASSOCIATED WITH HIGHER LEVELS OF UPPER ABDOMINAL PAIN/DISCOMFORT (SCORES ≥3 vs. <3) | ||||
|---|---|---|---|---|
| Characteristic | Odds Ratio | 95% Confidence Interval |
P | |
| Demographic and clinical factors | Idiopathic etiology | 2.16 | 1.08, 4.31 | 0.029 |
| Acute symptom onset | 1.56 | 0.79, 3.08 | 0.199 | |
| Initial infectious prodrome | 0.35 | 0.15, 0.83 | 0.017 | |
| Gastroparesis severity measures |
Clinician-rated severity: Grade 2 vs. Grade 1 Grade 3 vs. Grade 1 |
1.23 0.68 |
0.51, 2.95 0.24, 1.93 |
0.29 |
| Overall GCSI | 1.14 |
1.09, 1.20 |
<0.001 |
|
|
PAGI-SYM: Constipation Diarrhea |
1.44 1.06 |
1.16, 1.77 0.86, 1.30 |
0.001 0.57 |
|
| Quality of life measures | PAGI-QOL | 0.58 | 0.37, 0.92 | 0.021 |
| SF-36 Physical component | 0.96 | 0.93, 1.00 | 0.049 | |
| Parameters of psychological dysfunction | BDI | 0.98 | 0.94, 1.03 | 0.48 |
| STAI Y1 | 1.03 | 0.99, 1.06 | 0.142 | |
| Gastric emptying | Gastric retention at 2 hrs | 0.99 | 0.98, 1.01 | 0.39 |
| Medication use | Prokinetics Antiemetics Opiates Neuropathic pain modulators Antidepressants |
0.59 0.62 1.01 1.22 1.36 |
0.30, 1.16 0.30, 1.28 0.51, 1.99 0.52, 2.87 0.71, 2.61 |
0.124 0.196 0.99 0.65 0.35 |
| B: CHARACTERISTICS INDEPENDENTLY ASSOCIATED WITH PREDOMINANT ABDOMINAL PAIN/DISCOMFORT VS. PREDOMINANT NAUSEA/VOMITING | ||||
|---|---|---|---|---|
| Characteristic | Odds Ratio | 95% Confidence Interval |
P | |
| Demographic and clinical factors | Idiopathic etiology | 1.66 | 0.74, 3.69 | 0.22 |
| Acute symptom onset | 0.73 | 0.37, 1.46 | 0.37 | |
| Initial infectious prodrome | 0.71 | 0.29, 1.75 | 0.46 | |
| Gastroparesis severity measures |
Clinician-rated severity: Grade 2 vs. Grade 1 Grade 3 vs. Grade 1 |
1.03 1.42 |
0.32, 3.33 0.40, 5.08 |
0.69 |
| GCSI | 0.91 | 0.86, 0.95 | <0.001 | |
|
PAGI-SYM: Constipation Diarrhea |
1.03 0.91 |
0.83, 1.29 0.74, 1.12 |
0.76 0.36 |
|
| Quality of life measures | PAGI-QOL | 0.52 | 0.33, 0.82 | 0.005 |
| SF-36 – Physical component | 0.98 | 0.94, 1.02 | 0.28 | |
| Parameters of psychological dysfunction | BDI | 0.97 | 0.92, 1.01 | 0.160 |
| STAI – Y1 | 1.02 | 0.99, 1.06 | 0.27 | |
| Gastric emptying | Gastric retention at 2 hours | 1.01 | 0.99, 1.02 | 0.54 |
| Quality of life measures | Prokinetics Antiemetics Opiates Neuropathic pain modulators Antidepressants |
0.60 0.21 3.38 0.60 1.52 |
0.30, 1.21 0.09, 0.48 1.61, 7.10 0.25, 1.47 0.75, 3.09 |
0.154 <0.001 0.001 0.27 0.25 |
*
Model adjusted for age, sex, and self-reported race and ethnicity
GCSI: Gastroparesis Cardinal Symptom Index
PAGI-SYM: Patient Assessment of Upper Gastrointestinal Disorders Symptoms
PAGI-QOL: Patient Assessment of Upper Gastrointestinal Disorders Quality of Life
SF-36: Short Form-36
Hosmer-Lemeshow Goodness-of-Fit P=0.47
*
Model adjusted for age, sex, and self-reported race and ethnicity
GCSI: Gastroparesis Cardinal Symptom Index
PAGI-SYM: Patient Assessment of Upper Gastrointestinal Disorders Symptoms
PAGI-QOL: Patient Assessment of Upper Gastrointestinal Disorders Quality of Life
SF-36: Short Form-36
Hosmer-Lemeshow Goodness-of-Fit P=0.84