Table 1.
Results of mass spectrometry of proteins pulled down by immunoprecipitation of Py-ICPa
| Gene ID | Descriptionb | Times observedc (N=5) |
Peptide hitsd |
|---|---|---|---|
| PY03424 | Cysteine protease inhibitor ICP | 5 | 34, 24, 6, 4, 4 |
| PY00783 | Cysteine protease berghepain-2. Ortholog of Falcipain 2Pf and 3Pf. |
5 | 11, 7, 10, 10, 3 |
| PY03267 | Unknown protein, putative. Orthologs are annotated as Golgi organization & biogenesis factorPf and proteosome regulatory componentPb,Pc. |
2 | 1, 3 |
| PY01075 e | GTPase, Rab18, putative. | 2 | 1, 2 |
| PY05916 | Multiprotein bridging factor type 1, putative. | 2 | 2, 2 |
| PY01361 | Conserved Plasmodium protein, unknown function. Contains WD-40 domains. |
2 | 1, 2 |
a
Proteins were present in at least two immune-precipitations, but not in any of the experimental controls. List does not include ribosomal or heatshock proteins.
b
Description based on annotations in PlasmoDB. The annotations of orthologous proteins from P. falciparum (Pf), P. berghei (Pb) and P. chabaudi (Pc) are denoted when available.
c
Determined by the presence of protein in five independent experiments
d
Total peptide hits observed in each pulldown where protein was observed.
e
This gene is currently misannotated for P. yoelii. Peptide hits correspond to the protein encoded by the syntenic P. berghei gene PBANKA_122330