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. 2013 Jul 31;2:120. Originally published 2013 May 2. [Version 2] doi: 10.12688/f1000research.2-120.v2

PMC3907159.1; 2013 May 2
PMC3907159.2; 2013 Jul 31

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Copyright: © 2013 Lin LL et al.

This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Data associated with the article are available under the terms of the Creative Commons Zero "No rights reserved" data waiver (CC0 1.0 Public domain dedication).

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Figure 2. — Channel width and velocity were varied to optimise the microbiopsy device configuration. Total DNA was used as a surrogate for sample size. Panel ( a) shows the DNA extracted from device with varying channel width and that the maximum amount of DNA was collected with 0.15 mm channel width. Panel ( b) displays high resolution scanning electron microscopic images showing different channel widths of the microbiopsy device. Panel ( c) shows the level of pain volunteers reported when different channel width microbiopsies were used. Panel ( d) shows the varying velocity applied and that the maximum amount of DNA was collected when the device was applied at 16.6 m/s. Panel ( e) shows the level of pain volunteers reported when application velocity was varied.