Table 1. Summary of final study design.

Baseline	Weeks 1–2	2 week visit	Weeks 3–4	4 week visit
Clinical evaluation; randomize	Placebo 2.5mg 5mg	Clinical evaluation; ↑ dopaminometic, if indicated	Placebo 2.5mg 5mg	Clinical evaluation; return to routine clinical care

This table summarizes the study design and timing of assessments and interventions for the last 19 subjects enrolled in the study. ↑ dopaminometic: dose increase allowed for antiparkinsonian medication, if parkinsonism had worsened since starting the study. See Methods and Figure 1 for further details.