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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Neurogastroenterol Motil. 2013 Nov 22;26(2):272–282. doi: 10.1111/nmo.12261

Figure 3. Ghrelin increases the frequency of sEPSCs but not sIPSCs.

Figure 3

A: Six overlapping consecutive traces of sEPSCs (left) and sIPSCs (right) in DMV neurons voltage clamped at −60mV and −50mV, respectively. Ghrelin (100nM) was applied by superfusion for at least 3 minutes, or until the response reached plateau. Note that ghrelin increased the frequency of sEPSCs in a reversible manner, whereas ghrelin had no effect on sIPSC frequency.

B: computer generated graphics from the same neuron in A (left) showing the ghrelin-induced alteration in sEPSC frequency (left) but not amplitude (right).

C: Graphical summary of the effects of ghrelin to increase sEPSC frequency but not amplitude