. Author manuscript; available in PMC: 2014 Jan 30.

Published in final edited form as: Blood Rev. 2011 Feb 3;25(3):107–112. doi: 10.1016/j.blre.2011.01.005

Table 5.

TP53 in plasma cell leukemia.

p53 pathway	N	pPCL	sPCL	P value
Allelic p53 mutation	25	25	23	–
Allelic p53 deletion	20	50	75	0.37
Combined	15	56	83	0.58
biallelic p53 loss	15	11	33	0.52
MDM2 amplification	18	0	0	–
PTEN Deletion	18	8	33	0.24
RAS mutation	24	27	15	0.63
p16 methylation	24	27	38	0.68
p14 methylation	27	0	29	0.10

Modified from Tiedemann et al 2008.⁷