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. 2014 Jan 7;106(1):124–133. doi: 10.1016/j.bpj.2013.10.042

Figure 3.

Figure 3

(a) Plot of the cubic function describing Veff at x1 = 0, the bottom of the well at u = 0, and the top of the energy barrier of height Δ at u = u0. (Dashed lines) Increasing applied force F, labeled on plot. (b) Contour plot of Veff(x1,u). (Darker areas) Lower energy values. In this plot we have chosen the values of κ˜=κu02/Δ=0.4 and f˜=Fu0/Δ=0.3. The latter value corresponds to the 0.2 of the critical force FC. (Solid arrows) Approximation used to the preferred path OACB along the potential surface; (dashed line) example of another path, with lower potential barrier but an effectively much lower rate. To see this figure in color, go online.