Figure 4.

Force-curve alignment for Molecules 1 and 2. (Upper) Experimental force versus trap displacement for two unzipping experiments (Molecules 1 and 2) in Huguet et al. (4). (Middle) Coincidence between the force curves is strongly improved by our alignment procedure. We first globally shift the curve of Molecule 2 by $\simeq 0.5$ pN, then apply the Matlab routine for aligning the force curves along the basepair index axis, described in the main text. (Lower) Difference, $\Delta g^{SP}\left(n\right)$, between the SP free energies inferred from Molecules 1 and 2 after alignment. To see this figure in color, go online.